NETosis in Broncho-Alveolar Lavage-Fluid (BAL-f) from Bronchiolitis Obliterans Syndrome (BOS) Patients
نویسندگان
چکیده
منابع مشابه
Bronchiolitis Obliterans Syndrome (BOS) Following Lung Transplant.
The main change seen with BOS is scarring of the small airways of transplanted lung(s). This scarring leads to narrowing of the airways, limiting airflow with loss of lung function. Early after the onset of BOS, a person may not have any symptoms, but will develop breathlessness and chronic cough as BOS gets worse. There are different stages of BOS based on lung function results. Some people de...
متن کاملYellow Broncho-alveolar Lavage Fluid in Eosinophilic Pneumonia
A 34-year-old man with bronchial asthma was introduced to our clinic because his blood tests showed a white blood cell count of 25,200/μL with a differential of 70% eosinophils, and chest computed tomography revealed nonsegmental multi-lobar consolidation. Bronchoscopy was performed and yellow broncho-alveolar lavage fluid (BALF) was collected (Picture 1). The supernatant of BALF was still yell...
متن کاملElevated Peptides in Lung Lavage Fluid Associated with Bronchiolitis Obliterans Syndrome
OBJECTIVE The objective of this discovery-level investigation was to use mass spectrometry to identify low mass compounds in bronchoalveolar lavage fluid from lung transplant recipients that associate with bronchiolitis obliterans syndrome. EXPERIMENTAL DESIGN Bronchoalveolar lavage fluid samples from lung transplant recipients were evaluated for small molecules using ESI-TOF mass spectrometr...
متن کاملBronchiolitis obliterans syndrome in lung transplant recipients is associated with increased neutrophil activity and decreased antioxidant status in the lung.
Long-term survival of lung transplant recipients is limited by the advent of obliterative bronchiolitis and irreversible airways obstruction, e.g. bronchiolitis obliterans syndrome (BOS). This study investigated whether inflammatory cells and their activation markers were increased in bronchoalveolar lavage (BAL) and transbronchial biopsies (TBB) from patients with BOS. Levels of antioxidants i...
متن کاملSoluble form of fas and fas ligand in BAL fluid from patients with pulmonary fibrosis and bronchiolitis obliterans organizing pneumonia.
STUDY OBJECTIVES The Fas-Fas ligand (FasL) pathway is a representative system of apoptosis-signaling receptor molecules. We previously described that this pathway may play an important role in the pathogenesis of fibrosing lung diseases. In this study, we hypothesized that soluble form of Fas (sFas) and FasL (sFasL) may also be associated with this disorder. MEASUREMENTS AND RESULTS We measur...
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ژورنال
عنوان ژورنال: The Journal of Heart and Lung Transplantation
سال: 2021
ISSN: 1053-2498
DOI: 10.1016/j.healun.2021.01.859